Bioassay-guided isolation of the antimicrobial compounds of Coleus amboinicus Loureiro (Lamiaceae)
Roberta Dizon-Lauzon and Linda B. Mabesa ABSTRACT The essential oil of the aerial part of Coleus amboinicus showed antibacterial activity against Bacillus subtilis (gram +) and Pseudomonas fluorescens (gram -) and antifungal activity against Cladosporium cucumerinum. Bioassay-guided fractionation revealed that carvacrol and ß-caryophyllene-4,5-oxide were the major contributors to the antimicrobial activity of the essential oil. …